Explore dataset by tumor types Show Annotation Activity

Click on a tumor type to see what genes are significantly mutated in it (and other details).
Acute myeloid leukemia
AML
196 patients
Bladder
BLCA
99 patients
Breast
BRCA
892 patients
Carcinoid
CARC
54 patients
Chronic lymphocytic leukemia
CLL
159 patients
Colorectal
CRC
233 patients
Diffuse large B-cell lymphoma
DLBCL
58 patients
Esophageal adenocarcinoma
ESO
141 patients
Glioblastoma multiforme
GBM
291 patients
Head and neck
HNSC
384 patients
Kidney clear cell
KIRC
417 patients
Lung adenocarcinoma
LUAD
405 patients
Lung squamous cell carcinoma
LUSC
178 patients
Medulloblastoma
MED
92 patients
Melanoma
MEL
118 patients
Multiple myeloma
MM
207 patients
Neuroblastoma
NB
81 patients
Ovarian
OV
316 patients
combined cohort
PanCan
4742 patients
Prostate
PRAD
138 patients
Rhabdoid tumor
RHAB
35 patients
Endometrial
UCEC
248 patients

Explore dataset by Genes

Click on a gene name to see what tumor types it is significantly mutated in (and other details).
TP53
36% of all patients
PIK3CA
14% of all patients
PTEN
7% of all patients
KRAS
7% of all patients
APC
6% of all patients
MLL3
6% of all patients
FAT1
6% of all patients
MLL2
5% of all patients
ARID1A
5% of all patients
VHL
4% of all patients
PBRM1
4% of all patients
NF1
4% of all patients
EGFR
4% of all patients
ATM
4% of all patients
PIK3R1
3% of all patients
BRAF
3% of all patients
CDKN2A
3% of all patients
SETD2
3% of all patients
CREBBP
3% of all patients
FBXW7
3% of all patients
SPEN
3% of all patients
MTOR
3% of all patients
RB1
2% of all patients
SMARCA4
2% of all patients
NOTCH1
2% of all patients

Explore by Figures

Or browse clickable interactive versions of figures from the paper.
Figure 2: Genes in each tumor type
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Figure 3: Tumor-type-specific and pan-cancer genes
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Figure 5: Discovery power in each tumor type
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Power Calculator
Powercalc
Figure S1: Background mutation frequencies across cancer
Figs1.thumbnail

Cite TumorPortal

Using this data? Please cite  Lawrence et al. Nature (2014)

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