UCEC - Endometrial Back

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iCoMut Beta for


Highly significantly mutated genes
PTEN
163 patients (65%)
PIK3CA
133 patients (53%)
PIK3R1
84 patients (33%)
ARID1A
83 patients (33%)
TP53
70 patients (28%)
KRAS
54 patients (21%)
CTCF
46 patients (18%)
ZFHX3
45 patients (18%)
FBXW7
40 patients (16%)
FGFR2
37 patients (14%)
ARHGAP35
36 patients (14%)
PPP2R1A
30 patients (12%)
CCND1
17 patients (6%)
ERBB3
17 patients (6%)
ZNF471
16 patients (6%)
ING1
13 patients (5%)
Significantly mutated genes
CTNNB1
77 patients (31%)
FAT1
42 patients (16%)
BCOR
36 patients (14%)
CHD4
36 patients (14%)
ANK3
33 patients (13%)
ARID5B
29 patients (11%)
POLE
28 patients (11%)
SACS
27 patients (10%)
CUX1
25 patients (10%)
EP300
22 patients (8%)
SPOP
21 patients (8%)
GNPTAB
21 patients (8%)
MORC4
20 patients (8%)
DNER
19 patients (7%)
INPPL1
19 patients (7%)
SGK1
16 patients (6%)
ADNP
15 patients (6%)
SOS1
15 patients (6%)
SLC1A3
14 patients (5%)
TCP11L2
14 patients (5%)
RSBN1L
13 patients (5%)
TBL1XR1
13 patients (5%)
CAP2
13 patients (5%)
KLHL8
12 patients (4%)
PPM1D
12 patients (4%)
ZNF620
11 patients (4%)
SOX17
11 patients (4%)
SELP
11 patients (4%)
DIAPH1
10 patients (4%)
TTLL9
10 patients (4%)
MICALCL
10 patients (4%)
NRAS
9 patients (3%)
EIF2S2
9 patients (3%)
AKT1
8 patients (3%)
ZRANB3
8 patients (3%)
TAP1
8 patients (3%)
SLC44A3
7 patients (2%)
MYCN
7 patients (2%)
TXNDC8
7 patients (2%)
ALKBH6
7 patients (2%)
CCDC6
6 patients (2%)
TPX2
6 patients (2%)
Genes near significance
MLL4
34 patients (13%)
ATM
31 patients (12%)
MTOR
27 patients (10%)
MGA
26 patients (10%)
COL5A1
25 patients (10%)
RASA1
22 patients (8%)
RB1
20 patients (8%)
ZNF334
19 patients (7%)
CCDC144A
18 patients (7%)
CASP8
18 patients (7%)
RAB3GAP1
17 patients (6%)
ZNF606
16 patients (6%)
NFE2L2
16 patients (6%)
TP53BP1
15 patients (6%)
APAF1
14 patients (5%)
EDC4
13 patients (5%)
JAKMIP2
12 patients (4%)
MECOM
12 patients (4%)
PBRM1
12 patients (4%)
TBRG4
11 patients (4%)
ZNF485
11 patients (4%)
METTL14
11 patients (4%)
KRT35
10 patients (4%)
FLT3
10 patients (4%)
GFAP
9 patients (3%)
ZNF263
8 patients (3%)
CAB39L
8 patients (3%)
ERBB2
8 patients (3%)
TDRD10
8 patients (3%)
AHCYL1
7 patients (2%)
LGMN
7 patients (2%)
OR8B8
7 patients (2%)
CDKN1B
7 patients (2%)
RRAS2
4 patients (1%)
NAA38
4 patients (1%)
TMEM55A
4 patients (1%)
Click on a gene to see details.

Notes


• Gene name color indicates: known cancer genes | highly compelling novel candidate cancer genes | other candidates

Data details


Mutation list for UCEC
Q-Q plots for UCEC