HNSC - Head and neck Back

External References: Wikipedia National Cancer Institute Google Scholar

iCoMut Beta for


Highly significantly mutated genes
TP53
258 patients (67%)
CDKN2A
78 patients (20%)
FAT1
77 patients (20%)
PIK3CA
70 patients (18%)
NOTCH1
65 patients (16%)
MLL2
59 patients (15%)
NSD1
39 patients (10%)
CASP8
33 patients (8%)
NFE2L2
21 patients (5%)
AJUBA
18 patients (4%)
EPHA2
16 patients (4%)
HRAS
15 patients (3%)
ZNF750
15 patients (3%)
TGFBR2
12 patients (3%)
HLA-A
12 patients (3%)
PTEN
11 patients (2%)
RAC1
10 patients (2%)
RHOA
6 patients (1%)
Significantly mutated genes
EP300
27 patients (7%)
RASA1
16 patients (4%)
CTCF
12 patients (3%)
HLA-B
9 patients (2%)
B2M
7 patients (1%)
MAP4K3
7 patients (1%)
IPO7
5 patients (1%)
OTUD7A
3 patients (0%)
Genes near significance
MLL3
26 patients (6%)
NCOR1
14 patients (3%)
ARHGAP35
13 patients (3%)
LCP1
12 patients (3%)
RB1
11 patients (2%)
ARID2
11 patients (2%)
ASXL1
10 patients (2%)
PBRM1
9 patients (2%)
KDM6A
8 patients (2%)
IRF6
8 patients (2%)
SMAD4
7 patients (1%)
RBM5
6 patients (1%)
ELF4
5 patients (1%)
MAPK1
4 patients (1%)
Click on a gene to see details.

Notes


• Gene name color indicates: known cancer genes | highly compelling novel candidate cancer genes | other candidates

Data details


Mutation list for HNSC
Q-Q plots for HNSC