ELF4 Back

E74-like factor 4 (ets domain transcription factor)

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NCBI Description of ELF4

The protein encoded by this gene is a transcriptional activator that binds and activates the promoters of the CSF2, IL3, IL8, and PRF1 genes. The encoded protein is involved in natural killer cell development and function, innate immunity, and induction of cell cycle arrest in naive CD8+ cells. Two transcript variants encoding the same protein have been found for this gene.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ELF4 is highly significantly mutated in
ELF4 is significantly mutated in
ELF4 is near significance in
Head and neck
5 patients (1%)

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ELF4