OTU domain containing 7A

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NCBI Description of OTUD7A

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008].

Community Annotation of OTUD7A Add / Edit OTUD7A: Annotations

No community annotations yet for OTUD7A.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


OTUD7A is highly significantly mutated in
OTUD7A is significantly mutated in
Head and neck
3 patients (0%)
OTUD7A is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for OTUD7A