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GATA binding protein 3

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NCBI Description of GATA3
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia.

Community Annotation of GATA3 Add / Edit GATA3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

GATA3 is highly significantly mutated in
Breast
BRCA
84 patients (9%)
combined cohort
PanCan
119 patients (2%)
GATA3 is significantly mutated in
GATA3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for GATA3