ZRSR2 Back

zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

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NCBI Description of ZRSR2

This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZRSR2 is highly significantly mutated in
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ZRSR2 is significantly mutated in
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ZRSR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ZRSR2