ZNF397 Back

zinc finger protein 397

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NCBI Description of ZNF397
This gene encodes a protein with a N-terminal SCAN domain, and the longer isoform contains nine C2H2-type zinc finger repeats in the C-terminal domain. The protein localizes to centromeres during interphase and early prophase, and different isoforms can repress or activate transcription in transfection studies. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but their biological validity has not been determined.

Community Annotation of ZNF397 Add / Edit ZNF397: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZNF397 is highly significantly mutated in
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ZNF397 is significantly mutated in
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ZNF397 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ZNF397