ZNF346 Back

zinc finger protein 346

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NCBI Description of ZNF346

The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZNF346 is highly significantly mutated in
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ZNF346 is significantly mutated in
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ZNF346 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ZNF346