ZNF10 Back

zinc finger protein 10

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NCBI Description of ZNF10

The protein encoded by this gene contains a C2H2 zinc finger, and has been shown to function as a transcriptional repressor. The Kruppel-associated box (KRAB) domain of this protein is found to be responsible for its transcriptional repression activity. RING finger containing protein TIF1 was reported to interact with the KRAB domain, and may serve as a mediator for the repression activity of this protein.

Community Annotation of ZNF10 Add / Edit ZNF10: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZNF10 is highly significantly mutated in
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ZNF10 is significantly mutated in
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ZNF10 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ZNF10