ZMIZ2 Back

zinc finger, MIZ-type containing 2

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NCBI Description of ZMIZ2
ZMIZ2 and ZMIZ1 (MIM 607159) are members of a PIAS (see MIM 603566)-like family of proteins that interact with nuclear hormone receptors. ZMIZ2 interacts with androgen receptor (AR; MIM 313700) and enhances AR-mediated transcription (Huang et al., 2005 [PubMed 16051670]).[supplied by OMIM, May 2010].

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZMIZ2 is highly significantly mutated in
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ZMIZ2 is significantly mutated in
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ZMIZ2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ZMIZ2