ZIC1 Back

Zic family member 1 (odd-paired homolog, Drosophila)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of ZIC1

This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.

Community Annotation of ZIC1 Add / Edit ZIC1: Annotations

No community annotations yet for ZIC1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZIC1 is highly significantly mutated in
(none)
ZIC1 is significantly mutated in
(none)
ZIC1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ZIC1