ZFYVE26 Back

zinc finger, FYVE domain containing 26

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NCBI Description of ZFYVE26
This gene encodes a protein which contains a FYVE zinc finger binding domain. The presence of this domain is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZFYVE26 is highly significantly mutated in
(none)
ZFYVE26 is significantly mutated in
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ZFYVE26 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ZFYVE26