ZFYVE16 Back

zinc finger, FYVE domain containing 16

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NCBI Description of ZFYVE16

The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of the molecule (Seet et al., 2004 [PubMed 14613930]).[supplied by OMIM, Mar 2008].

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ZFYVE16 is highly significantly mutated in
ZFYVE16 is significantly mutated in
ZFYVE16 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ZFYVE16