ZFP36L2 Back

zinc finger protein 36, C3H type-like 2

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NCBI Description of ZFP36L2
This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

Community Annotation of ZFP36L2 Add / Edit ZFP36L2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZFP36L2 is highly significantly mutated in
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ZFP36L2 is significantly mutated in
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ZFP36L2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ZFP36L2