ZC3HAV1 Back

zinc finger CCCH-type, antiviral 1

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NCBI Description of ZC3HAV1

This gene encodes a CCCH-type zinc finger protein that is thought to prevent infection by retroviruses. Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection. Alternative splicing occurs at this locus and two variants, each encoding distinct isoforms, are described.

Community Annotation of ZC3HAV1 Add / Edit ZC3HAV1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ZC3HAV1 is highly significantly mutated in
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ZC3HAV1 is significantly mutated in
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ZC3HAV1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ZC3HAV1