ZAR1 Back

zygote arrest 1

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NCBI Description of ZAR1

The female gamete, the oocyte, serves the distinct purpose of transmitting the maternal genome and other maternal factors critical for postovulation events. Oocytes have diverse functions in ovarian folliculogenesis, fertilization, and embryogenesis. ZAR1 is an oocyte-specific gene that appears to function at the oocyte-to-gamete transition (Wu et al., 2003 [PubMed 12539046]).[supplied by OMIM, Mar 2008].

Community Annotation of ZAR1 Add / Edit ZAR1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


ZAR1 is highly significantly mutated in
ZAR1 is significantly mutated in
ZAR1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for ZAR1