YWHAB Back

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

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NCBI Description of YWHAB
This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.

Community Annotation of YWHAB Add / Edit YWHAB: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

YWHAB is highly significantly mutated in
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YWHAB is significantly mutated in
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YWHAB is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for YWHAB