YEATS4 Back

YEATS domain containing 4

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NCBI Description of YEATS4

The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

YEATS4 is highly significantly mutated in
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YEATS4 is significantly mutated in
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YEATS4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for YEATS4