exportin, tRNA (nuclear export receptor for tRNAs)

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NCBI Description of XPOT

This gene encodes a protein belonging to the RAN-GTPase exportin family that mediates export of tRNA from the nucleus to the cytoplasm. Translocation of tRNA to the cytoplasm occurs once exportin has bound both tRNA and GTP-bound RAN.

Community Annotation of XPOT Add / Edit XPOT: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


XPOT is highly significantly mutated in
XPOT is significantly mutated in
XPOT is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for XPOT