XCL1 Back

chemokine (C motif) ligand 1

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NCBI Description of XCL1

This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


XCL1 is highly significantly mutated in
XCL1 is significantly mutated in
XCL1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for XCL1