WNT8A Back

wingless-type MMTV integration site family, member 8A

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NCBI Description of WNT8A
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and may be implicated in development of early embryos as well as germ cell tumors. It encodes a protein which shows 81% amino acid identity to the mouse Wnt8A protein.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WNT8A is highly significantly mutated in
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WNT8A is significantly mutated in
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WNT8A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WNT8A