WNT2B Back

wingless-type MMTV integration site family, member 2B

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NCBI Description of WNT2B

This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternatively spliced transcript variants.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


WNT2B is highly significantly mutated in
WNT2B is significantly mutated in
WNT2B is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for WNT2B