WFIKKN1 Back

WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of WFIKKN1
This gene encodes a secreted multidomain protein consisting of a signal peptide, a WAP domain, a follistatin domain, an immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. These domains have been implicated frequently in inhibition of various types of proteases, suggesting that the encoded protein may be a multivalent protease inhibitor and may control the action of multiple types of serine proteases as well as metalloproteinases.

Community Annotation of WFIKKN1 Add / Edit WFIKKN1: Annotations

No community annotations yet for WFIKKN1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WFIKKN1 is highly significantly mutated in
(none)
WFIKKN1 is significantly mutated in
(none)
WFIKKN1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WFIKKN1