WFDC9 Back

WAP four-disulfide core domain 9

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NCBI Description of WFDC9
The WAP-type four-disulfide core (WFDC) domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many members of the WFDC domain family. This gene encodes a protein which contains a WFDC domain, and is thus a member of the WFDC domain family. This gene and several other gene family members are clustered at 20q13.12.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WFDC9 is highly significantly mutated in
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WFDC9 is significantly mutated in
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WFDC9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WFDC9