WDR66 Back

WD repeat domain 66

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NCBI Description of WDR66
This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants.

Community Annotation of WDR66 Add / Edit WDR66: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WDR66 is highly significantly mutated in
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WDR66 is significantly mutated in
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WDR66 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WDR66