WDR1 Back

WD repeat domain 1

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NCBI Description of WDR1
This gene encodes a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. The encoded protein may help induce the disassembly of actin filaments. Two transcript variants encoding different isoforms have been found for this gene.

Community Annotation of WDR1 Add / Edit WDR1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WDR1 is highly significantly mutated in
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WDR1 is significantly mutated in
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WDR1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WDR1