NCBI Description of WDFY3
|This gene encodes a phosphatidylinositol 3-phosphate-binding protein that functions as a master conductor for aggregate clearance by autophagy. This protein shuttles from the nuclear membrane to colocalize with aggregated proteins, where it complexes with other autophagic components to achieve macroautophagy-mediated clearance of these aggregated proteins. However, it is not necessary for starvation-induced macroautophagy.|
Community Annotation of WDFY3 Add / Edit WDFY3: Annotations
No community annotations yet for WDFY3.
Click on a tumor type to see its full list of significant genes.