WDFY1 Back

WD repeat and FYVE domain containing 1

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NCBI Description of WDFY1

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains a single FYVE domain and multiple WD40 repeats. This protein is localized to endosomes.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


WDFY1 is highly significantly mutated in
WDFY1 is significantly mutated in
WDFY1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for WDFY1