WBP5 Back

WW domain binding protein 5

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NCBI Description of WBP5
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein. This gene also encodes a domain with similarity to the transcription elongation factor A, SII-related family. Alternative splicing results in multiple transcript variants encoding a single isoform.

Community Annotation of WBP5 Add / Edit WBP5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WBP5 is highly significantly mutated in
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WBP5 is significantly mutated in
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WBP5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WBP5