WBP2 Back

WW domain binding protein 2

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NCBI Description of WBP2
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein, which binds to the WW domain of Yes kinase-associated protein by its PY motifs. The function of this protein has not been determined.

Community Annotation of WBP2 Add / Edit WBP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WBP2 is highly significantly mutated in
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WBP2 is significantly mutated in
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WBP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WBP2