WAC Back

WW domain containing adaptor with coiled-coil

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NCBI Description of WAC
The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known. Alternative splicing results in multiple transcript variants.

Community Annotation of WAC Add / Edit WAC: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

WAC is highly significantly mutated in
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WAC is significantly mutated in
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WAC is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for WAC