VTN Back

vitronectin

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NCBI Description of VTN

The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.

Community Annotation of VTN Add / Edit VTN: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VTN is highly significantly mutated in
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VTN is significantly mutated in
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VTN is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for VTN