VPS54 Back

vacuolar protein sorting 54 homolog (S. cerevisiae)

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NCBI Description of VPS54

This gene encodes for a protein that in yeast forms part of a trimeric vacuolar-protein-sorting complex that is required for retrograde transport of proteins from prevacuoles to the late Golgi compartment. As in yeast, mammalian Vps54 proteins contain a coiled-coil region and dileucine motifs. Alternative splicing results in multiple transcript variants encoding different isoforms

Community Annotation of VPS54 Add / Edit VPS54: Annotations

No community annotations yet for VPS54.
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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


VPS54 is highly significantly mutated in
VPS54 is significantly mutated in
VPS54 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for VPS54