VPS52 Back

vacuolar protein sorting 52 homolog (S. cerevisiae)

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NCBI Description of VPS52

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


VPS52 is highly significantly mutated in
VPS52 is significantly mutated in
VPS52 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for VPS52