VPS37C Back

vacuolar protein sorting 37 homolog C (S. cerevisiae)

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NCBI Description of VPS37C
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008].

Community Annotation of VPS37C Add / Edit VPS37C: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VPS37C is highly significantly mutated in
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VPS37C is significantly mutated in
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VPS37C is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for VPS37C