NCBI Description of VPS26A
|This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.|
Community Annotation of VPS26A Add / Edit VPS26A: Annotations
No community annotations yet for VPS26A.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.