VIL1 Back

villin 1

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NCBI Description of VIL1
This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon.

Community Annotation of VIL1 Add / Edit VIL1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VIL1 is highly significantly mutated in
(none)
VIL1 is significantly mutated in
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VIL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for VIL1