VCAM1 Back

vascular cell adhesion molecule 1

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NCBI Description of VCAM1
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.

Community Annotation of VCAM1 Add / Edit VCAM1: Annotations

No community annotations yet for VCAM1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VCAM1 is highly significantly mutated in
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VCAM1 is significantly mutated in
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VCAM1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for VCAM1