VAV2 Back

vav 2 guanine nucleotide exchange factor

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NCBI Description of VAV2

VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Community Annotation of VAV2 Add / Edit VAV2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


VAV2 is highly significantly mutated in
VAV2 is significantly mutated in
VAV2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for VAV2