VANGL2 Back

vang-like 2 (van gogh, Drosophila)

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NCBI Description of VANGL2
The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of VANGL2 Add / Edit VANGL2: Annotations

No community annotations yet for VANGL2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VANGL2 is highly significantly mutated in
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VANGL2 is significantly mutated in
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VANGL2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for VANGL2