VAMP1 Back

vesicle-associated membrane protein 1 (synaptobrevin 1)

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NCBI Description of VAMP1
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. VAMP1 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Multiple alternative splice variants that encode proteins with alternative carboxy ends have been described, but the full-length nature of some variants has not been defined.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

VAMP1 is highly significantly mutated in
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VAMP1 is significantly mutated in
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VAMP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for VAMP1