UXS1 Back

UDP-glucuronate decarboxylase 1

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NCBI Description of UXS1

This gene encodes an enyzme found in the perinuclear Golgi which catalyzes the synthesis of UDP-xylose used in glycosaminoglycan (GAG) synthesis on proteoglycans. The GAG chains are covalently attached to proteoglycans which participate in signaling pathways during development. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of UXS1 Add / Edit UXS1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


UXS1 is highly significantly mutated in
UXS1 is significantly mutated in
UXS1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for UXS1