USP25 Back

ubiquitin specific peptidase 25

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NCBI Description of USP25
Ubiquitin (MIM 191339) is a highly conserved 76-amino acid protein involved in regulation of intracellular protein breakdown, cell cycle regulation, and stress response. Ubiquitin is released from degraded proteins by disassembly of the polyubiquitin chains, which is mediated by ubiquitin-specific proteases (USPs), such as USP25 (Valero et al., 1999 [PubMed 10644437]).[supplied by OMIM, Mar 2008].

Community Annotation of USP25 Add / Edit USP25: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

USP25 is highly significantly mutated in
(none)
USP25 is significantly mutated in
(none)
USP25 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for USP25