UNC45A Back

unc-45 homolog A (C. elegans)

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NCBI Description of UNC45A

UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90 (HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002 [PubMed 12356907]; Chadli et al., 2006 [PubMed 16478993]).[supplied by OMIM, Mar 2008].

Community Annotation of UNC45A Add / Edit UNC45A: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UNC45A is highly significantly mutated in
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UNC45A is significantly mutated in
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UNC45A is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for UNC45A