UNC13A Back

unc-13 homolog A (C. elegans)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of UNC13A
This gene encodes a member of the UNC13 family. UNC13 proteins bind to phorbol esters and diacylglycerol and play important roles in neurotransmitter release at synapses. Single nucleotide polymorphisms in this gene may be associated with sporadic amyotrophic lateral sclerosis. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of UNC13A Add / Edit UNC13A: Annotations

No community annotations yet for UNC13A.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UNC13A is highly significantly mutated in
(none)
UNC13A is significantly mutated in
(none)
UNC13A is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for UNC13A