UNC119 Back

unc-119 homolog (C. elegans)

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NCBI Description of UNC119

This gene is specifically expressed in the photoreceptors in the retina. The encoded product shares strong homology with the C. elegans unc119 protein and it can functionally complement the C. elegans unc119 mutation. It has been localized to the photoreceptor synapses in the outer plexiform layer of the retina, and suggested to play a role in the mechanism of photoreceptor neurotransmitter release through the synaptic vesicle cycle. Two transcript variants encoding different isoforms have been described for this gene.

Community Annotation of UNC119 Add / Edit UNC119: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UNC119 is highly significantly mutated in
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UNC119 is significantly mutated in
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UNC119 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for UNC119