NCBI Description of UGT2B28
|This gene encodes a member of the uridine diphosphoglucuronosyltransferase protein family. The encoded enzyme catalyzes the transfer of glucuronic acid from uridine diphosphoglucuronic acid to a diverse array of substrates including steroid hormones and lipid-soluble drugs. This process, known as glucuronidation, is an intermediate step in the metabolism of steroids. Two transcript variants encoding different isoforms have been found for this gene. While both isoforms are targeted to the endoplasmic reticulum, only the longer isoform appears to be active.|
Community Annotation of UGT2B28 Add / Edit UGT2B28: Annotations
No community annotations yet for UGT2B28.
• "Mouse over" a mutation to see details.
Click on a tumor type to see its full list of significant genes.