UFSP2 Back

UFM1-specific peptidase 2

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NCBI Description of UFSP2

Like ubiquitin (see MIM 191339), ubiquitin-fold modifier-1 (UFM1; MIM 610553) must be processed by a protease before it can conjugate with its target proteins. UFSP2 is a thiol protease that specifically processes the C terminus of UFM1 (Kang et al., 2007 [PubMed 17182609]).[supplied by OMIM, Oct 2009].

Community Annotation of UFSP2 Add / Edit UFSP2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UFSP2 is highly significantly mutated in
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UFSP2 is significantly mutated in
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UFSP2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for UFSP2