UCN3 Back

urocortin 3 (stresscopin)

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NCBI Description of UCN3

This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II.

Community Annotation of UCN3 Add / Edit UCN3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

UCN3 is highly significantly mutated in
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UCN3 is significantly mutated in
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UCN3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for UCN3